Articles By Keyword

. "Bayesian design of a survival trial with a cured fraction using historical data.." Stat Med. 2018;37(26):3814-3831. Pub Med
. "Improved detection of epigenomic marks with mixed effects hidden Markov models.." Biometrics. 2019;75(4):1401-1413. Pub Med
. "Static and dynamic DNA loops form AP-1-bound activation hubs during macrophage development.." Mol Cell. 2017;67(6):1037-1048.e6. Pub Med
. "Biclustering with heterogeneous variance.." Proc Natl Acad Sci U S A. 2013;110(30):12253-8. Pub Med
. "Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs.." Nat Commun. 2019;10(1):309. Pub Med
. "Integrative pipeline for profiling DNA copy number and inferring tumor phylogeny.." Bioinformatics. 2018;34(12):2126-2128. Pub Med
. "Global copy number profiling of cancer genomes.." Bioinformatics. 2016;32(6):926-8. Pub Med
. "DiNAMIC: A method to identify recurrent DNA copy number aberrations in tumors.." Bioinformatics. 2011;27(5):678-85. Pub Med
. "Integrative gene set analysis of multi-platform data with sample heterogeneity.." Bioinformatics. 2014;30(11):1501-7. Pub Med
. "SCOPE: A normalization and copy-number estimation method for single-cell DNA sequencing.." Cell Syst. 2020;10(5):445-452.e6. Pub Med
. "SynthEx: a synthetic-normal-based DNA sequencing tool for copy number alteration detection and tumor heterogeneity profiling.." Genome Biol. 2017;18(1):66. Pub Med
. "CODEX2: Full-spectrum copy number variation detection by high-throughput DNA sequencing.." Genome Biol. 2018;19(1):202. Pub Med
. "Allele-specific copy-number discovery from whole-genome and whole-exome sequencing.." Nucleic Acids Res. 2015;43(14):e90. Pub Med
. "The association between copy number aberration, DNA methylation and gene expression in tumor samples.." Nucleic Acids Res. 2018;46(6):3009-3018. Pub Med
. "Association test using Copy Number Profile Curves (CONCUR) enhances power in rare copy number variant analysis.." PLoS Comput Biol. 2020;16(5):e1007797. Pub Med
. "A new method for detecting associations with rare copy-number variants.." PLoS Genet. 2015;11(10):e1005403. Pub Med
. "Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs.." Nat Commun. 2019;10(1):309. Pub Med
. "Integrative gene set analysis of multi-platform data with sample heterogeneity.." Bioinformatics. 2014;30(11):1501-7. Pub Med
. "Mapping eQTL by leveraging multiple tissues and DNA methylation.." BMC Bioinformatics. 2017;18(1):455. Pub Med
. "Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma.." Cancer Discov. 2017;7(10):1116-1135. Pub Med
. "Across-platform imputation of DNA methylation levels incorporating nonlocal information using penalized functional regression.." Genet Epidemiol. 2016;40(4):333-40. Pub Med
. "The association between copy number aberration, DNA methylation and gene expression in tumor samples.." Nucleic Acids Res. 2018;46(6):3009-3018. Pub Med
. "Intergenerational response to the endocrine disruptor vinclozolin is influenced by maternal genotype and crossing scheme.." Reprod Toxicol. 2018;78():9-19. Pub Med
. "Integrative analysis of sequencing and array genotype data for discovering disease associations with rare mutations.." Proc Natl Acad Sci U S A. 2015;112(4):1019-24. Pub Med
. "PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation.." Sci Transl Med. 2016;8(369):369ra175. Pub Med
. "Single-nucleotide resolution analysis of nucleotide excision repair of ribosomal DNA in humans and mice.." J Biol Chem. 2019;294(1):210-217. Pub Med
. "Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells.." J Biol Chem. 2019;294(15):5914-5922. Pub Med
. "Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs.." Nat Commun. 2019;10(1):309. Pub Med
. "Incorporating higher-order representative features improves prediction in network-based cancer prognosis analysis.." BMC Med Genomics. 2011;4():5. Pub Med
. "DiNAMIC: A method to identify recurrent DNA copy number aberrations in tumors.." Bioinformatics. 2011;27(5):678-85. Pub Med
. "Associating somatic mutations to clinical outcomes: a pan-cancer study of survival time.." Genome Med. 2019;11(1):37. Pub Med
. "Single-nucleotide resolution analysis of nucleotide excision repair of ribosomal DNA in humans and mice.." J Biol Chem. 2019;294(1):210-217. Pub Med
. "Improved detection of epigenomic marks with mixed effects hidden Markov models.." Biometrics. 2019;75(4):1401-1413. Pub Med
. "Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells.." J Biol Chem. 2019;294(15):5914-5922. Pub Med
. "Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy.." Nat Commun. 2020;11(1):6410. Pub Med
. "Pharmacogenetics, enzyme probes and therapeutic drug monitoring as potential tools for individualizing taxane therapy.." Pharmacogenomics. 2013;14(5):555-74. Pub Med
. "Quantifying center of pressure variability in chondrodystrophoid dogs.." Vet J. 2017;226():26-31. Pub Med
. "Translational studies of phenotypic probes for the mononuclear phagocyte system and liposomal pharmacology.." J Pharmacol Exp Ther. 2013;347(3):599-606. Pub Med
. "Time course and prognostic value of serum GFAP, pNFH, and S100β concentrations in dogs with complete spinal cord injury because of intervertebral disc extrusion.." J Vet Intern Med. 2019;33(2):726-734. Pub Med
. "Quantifying center of pressure variability in chondrodystrophoid dogs.." Vet J. 2017;226():26-31. Pub Med
. "CRM2DIM: A SAS macro for implementing the dual-agent Bayesian continual reassessment method.." Comput Methods Programs Biomed. 2019;176():211-223. Pub Med
. "Practical designs for Phase I combination studies in oncology.." J Biopharm Stat. 2016;26(1):150-66. Pub Med
. "Continual reassessment method with regularization in phase I clinical trials.." J Biopharm Stat. 2020;30(6):964-978. Pub Med
. "Selection of the initial design for the two-stage continual reassessment method.." J Biopharm Stat. 2017;27(3):495-506. Pub Med
. "Dose-finding designs for trials of molecularly targeted agents and immunotherapies.." J Biopharm Stat. 2017;27(3):477-494. Pub Med
. "Rapid enrollment design for finding the optimal dose in immunotherapy trials with ordered groups.." J Biopharm Stat. 2019;29(4):625-634. Pub Med
. "Seamless phase IIa/IIb and enhanced dose-finding adaptive design.." J Biopharm Stat. 2016;26(5):912-23. Pub Med
. "The rapid enrollment design for Phase I clinical trials.." Stat Med. 2016;35(15):2516-24. Pub Med
. "Superiority of combining two independent trials in interim futility analysis.." Stat Methods Med Res. 2020;29(2):522-540. Pub Med
. "Generation of a transcriptional radiation exposure signature in human blood using long-read nanopore sequencing.." Radiat Res. 2020;193(2):143-154. Pub Med